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| Registros recuperados : 100 | |
| 8. |  | FERREIRA, L. C.; MEYER, M. C.; TERAMOTO, A.; VENANCIO, W. S. Efeito de fungicidas na inibição do crescimento micelial de Sclerotinia sclerotiorum isolado de soja. In: CONGRESSO BRASILEIRO DE SOJA, 5.; MERCOSOJA 2009, Goiânia. Resumos... Londrina: Embrapa Soja, 2009. p. 161, trab. 284. Editado por Adilson de Oliveira Júnior, Odilon Ferreira Saraiva, Clara Beatriz Hoffmann Campo, César de Castro.| Biblioteca(s): Embrapa Soja. |
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| 9. | | VENÂNCIO, W. S.; BEGLIOMINI, E.; RODRIGUES, M. A. T.; MEYER, M. C.; BUFFARA, M. A. Desempenho do fungicida BAS 512 14F no controle químico da ferrugem asiática da soja (Phakopsora pachyrhizi). Tropical Plant Pathology, Brasília, DF, v. 34, p. S112, ago. 2009. Suplemento, ref. 411. Edição dos Resumos do XLII Congresso Brasileiro de Fitopatologia; Annual Meeting of the Brazilian Phytopathological Society, Rio de Janeiro, ago. 2009.| Biblioteca(s): Embrapa Soja. |
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| 12. | | MEYER, M. C.; CAMPOS, H. D.; NUNES JUNIOR, J.; VENANCIO, W. S.; GODOY, C. V. Chemical control of white mold (Sclerotinia sclerotiorum) on soybean in Brazil. Acta Phytopathologica Sinica, v. 43, Supp., p. 137, 2013. Edition of the Abstracts 10th International Congress of Plant Pathology, Beijing, Aug. 2013.| Biblioteca(s): Embrapa Soja. |
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| 16. | | VENÂNCIO, W. S.; BEGLIOMINI, E.; RODRIGUES, M. A. T.; MEYER, M. C.; BUFFARA, M. A. Manejo de cercosporiose (Cercospora zeae-maydis) em milho (Zea mayz): efeito da época de controle sobre a produtividade. Tropical Plant Pathology, Brasília, DF, v. 34, p. S112, ago. 2009. Suplemento, ref. 412. Edição dos Resumos do XLII Congresso Brasileiro de Fitopatologia; Annual Meeting of the Brazilian Phytopathological Society, Rio de Janeiro, ago. 2009.| Biblioteca(s): Embrapa Soja. |
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| 18. | | MEYER, M. C.; COSTA, N. B.; FERREIRA, L. C.; NUNES JÚNIOR, J.; VENANCIO, W. S.; BEGLIOMINI, E. Comparison of the efficiency of soybean rust control by preventive and curative fungicides sprays, combined with different adjuvants, in Brazil. Plant Management Network, St. Paul, 2010. Edição do Proceedings do National Soybean Rust Symposium, New Orleans, 2009.| Biblioteca(s): Embrapa Soja. |
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| 19. | | MARZAROTTO, F. O.; VENANCIO, W. S.; SCAPIN, C. R.; BEGLIOMINI, E.; MEYER, M. C.; VENANCIO, R. M. Avaliação do controle de oídio (Microsphaeria diffusa) em soja (Glycine max) com diferentes doses dos fungicidas piraclostrobina + epoxiconazol e piraclostrobina 130 g.L-1 + metaconazol 80 g.L-1. Tropical Plant Pathology, Brasília, DF, v. 35, p. S117, ago. 2010. Suplemento, Ref. 03.171. Edição das palestras e resumos de trabalhos apresentados no 43 Congresso Brasileiro de Fitopatologia; do 43 Annual Meeting Of The Brazilian Phytopathology Society, Cuiabá, ago. 2010.| Biblioteca(s): Embrapa Soja. |
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| 20. | | SANTANA, F. M.; LAU, D.; SBALCHEIRO, C. C.; SUSSEL, A. A. B.; SEIXAS, C. D. S.; VENÂNCIO, W. S.; NICOLAU, M. Eficiência de fungicidas para controle da brusone de trigo: resultados dos ensaios cooperativos, safra 2016. Passo Fundo: Embrapa Trigo, 2019. 16 p. (Embrapa Trigo. Circular técnica online, 42).| Biblioteca(s): Embrapa Cerrados; Embrapa Soja; Embrapa Trigo. |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
09/11/2017 |
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Data da última atualização: |
21/11/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 3 |
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Autoria: |
SILVA, I. C. da; MAGALHAES, P. M. de; SOUSA, I. M. de O.; FOGLIO, M. A.; LEONARDECZ, E.; ESTEVES, S. N.; CHAGAS, A. C. de S. |
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Afiliação: |
Ives Charlie da Silva, UNESP; Pedro Melillo de Magalhães, UNICAMP; Ilza Maria de Oliveira Sousa, UNICAMP; Mary Ann Foglio, UNICAMP; Eduardo Leonardecz, UFSCar; SERGIO NOVITA ESTEVES, CPPSE; ANA CAROLINA DE SOUZA CHAGAS, CPPSE. |
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Título: |
Anthelmintic activity of Artemisia annua in sheepmodel. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Journal of Medicinal Plants Research, v. 11, n. 7, p. 137-143, 2017. |
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DOI: |
10.5897/JMPR2016.6318 |
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Idioma: |
Inglês |
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Conteúdo: |
Artemisia annua L. is a well-known source of artemisinin, an antimalarial drug. This compound has been used in traditional medicine to treat malaria for many years. The anthelmintic property of A. annua has also been attributed to artemisinin, hence the belief that artemisinin could be useful as an alternative anthelmintic to control Haemonchus contortus in livestock. The present study focused on evaluating the anthelmintic activity of A. annua against H. contortus by oral administration on infected sheep in a controlled clinical trial. The trial was conducted using 24 male sheep of the Santa Inês breed, with average weight of 20 kg, artificially infected with H. contortus (Embrapa 2010 isolate). The animals were kept in metabolic cages and randomly divided into four homogeneous groups with six animals each, being: (T1) negative control (untreated), (T2) positive control: 10 mg/kg BW of levamisole phosphate, (T3) fed 10% A. annua (0.2% BW), (T4) fed 20% A. annua (0.4% BW). EPG counts were conducted on days -3, -2, -1, 0 (treatment day), 3, 7, 10, 14, 17, 21, 24 and 28 post-treatment. After extraction of the artemisinin in plant material, it was quantified in triplicate and analyzed by high-performance liquid chromatography with infrared detection. The average efficacy in the positive control treated with levamisole was 89%. Moderate anthelmintic efficacy against H. contortus was observed in the groups fed 0.2 and 0.4% BW A. annua for 30 days (32.9 and 14.8%, respectively), mainly from day 21 post treatment (47.1 and 25.2%, respectively). At the highest dose, the animals avoided eating due to the compound?s bitter taste. It is concluded that A. annua presents moderate anthelmintic activity in sheep in both doses. The lowest dose was accepted by animals and seems to have practical use. Oral administration was safe and after further in vivo trials could be introduced in organic farms in tropical countries. MenosArtemisia annua L. is a well-known source of artemisinin, an antimalarial drug. This compound has been used in traditional medicine to treat malaria for many years. The anthelmintic property of A. annua has also been attributed to artemisinin, hence the belief that artemisinin could be useful as an alternative anthelmintic to control Haemonchus contortus in livestock. The present study focused on evaluating the anthelmintic activity of A. annua against H. contortus by oral administration on infected sheep in a controlled clinical trial. The trial was conducted using 24 male sheep of the Santa Inês breed, with average weight of 20 kg, artificially infected with H. contortus (Embrapa 2010 isolate). The animals were kept in metabolic cages and randomly divided into four homogeneous groups with six animals each, being: (T1) negative control (untreated), (T2) positive control: 10 mg/kg BW of levamisole phosphate, (T3) fed 10% A. annua (0.2% BW), (T4) fed 20% A. annua (0.4% BW). EPG counts were conducted on days -3, -2, -1, 0 (treatment day), 3, 7, 10, 14, 17, 21, 24 and 28 post-treatment. After extraction of the artemisinin in plant material, it was quantified in triplicate and analyzed by high-performance liquid chromatography with infrared detection. The average efficacy in the positive control treated with levamisole was 89%. Moderate anthelmintic efficacy against H. contortus was observed in the groups fed 0.2 and 0.4% BW A. annua for 30 days (32.9 and 14.8%, respectively), m... Mostrar Tudo |
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Thesaurus NAL: |
artemisinin; gastrointestinal nematodes; sesquiterpenoids. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
|
Marc: |
LEADER 02655naa a2200241 a 4500
001 2079284
005 2017-11-21
008 2017 bl uuuu u00u1 u #d
024 7 $a10.5897/JMPR2016.6318$2DOI
100 1 $aSILVA, I. C. da
245 $aAnthelmintic activity of Artemisia annua in sheepmodel.$h[electronic resource]
260 $c2017
520 $aArtemisia annua L. is a well-known source of artemisinin, an antimalarial drug. This compound has been used in traditional medicine to treat malaria for many years. The anthelmintic property of A. annua has also been attributed to artemisinin, hence the belief that artemisinin could be useful as an alternative anthelmintic to control Haemonchus contortus in livestock. The present study focused on evaluating the anthelmintic activity of A. annua against H. contortus by oral administration on infected sheep in a controlled clinical trial. The trial was conducted using 24 male sheep of the Santa Inês breed, with average weight of 20 kg, artificially infected with H. contortus (Embrapa 2010 isolate). The animals were kept in metabolic cages and randomly divided into four homogeneous groups with six animals each, being: (T1) negative control (untreated), (T2) positive control: 10 mg/kg BW of levamisole phosphate, (T3) fed 10% A. annua (0.2% BW), (T4) fed 20% A. annua (0.4% BW). EPG counts were conducted on days -3, -2, -1, 0 (treatment day), 3, 7, 10, 14, 17, 21, 24 and 28 post-treatment. After extraction of the artemisinin in plant material, it was quantified in triplicate and analyzed by high-performance liquid chromatography with infrared detection. The average efficacy in the positive control treated with levamisole was 89%. Moderate anthelmintic efficacy against H. contortus was observed in the groups fed 0.2 and 0.4% BW A. annua for 30 days (32.9 and 14.8%, respectively), mainly from day 21 post treatment (47.1 and 25.2%, respectively). At the highest dose, the animals avoided eating due to the compound?s bitter taste. It is concluded that A. annua presents moderate anthelmintic activity in sheep in both doses. The lowest dose was accepted by animals and seems to have practical use. Oral administration was safe and after further in vivo trials could be introduced in organic farms in tropical countries.
650 $aartemisinin
650 $agastrointestinal nematodes
650 $asesquiterpenoids
700 1 $aMAGALHAES, P. M. de
700 1 $aSOUSA, I. M. de O.
700 1 $aFOGLIO, M. A.
700 1 $aLEONARDECZ, E.
700 1 $aESTEVES, S. N.
700 1 $aCHAGAS, A. C. de S.
773 $tJournal of Medicinal Plants Research$gv. 11, n. 7, p. 137-143, 2017.
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